Description

2-Iodonicotinonitrile 98 is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive iodine handle and a versatile nitrile functional group for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of organic electronic materials, ligands for catalysis, and functional polymers.
• Cross-Coupling Reactions: Essential substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Negishi couplings to form new carbon-carbon bonds.
• Nitrile Transformation Chemistry: The nitrile group serves as a versatile handle for conversion into amides, acids, tetrazoles, and other heterocycles.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and molecular probes for biochemical research and diagnostic applications.

Basic Information

Product Name	2-Iodonicotinonitrile 98
CAS No.	490039-73-1
Molecular Formula	C6H3IN2
Molecular Weight	230.01 g/mol
Synonyms	2-Iodopyridine-3-carbonitrile; 3-Cyano-2-iodopyridine; 2-Iodo-3-cyanopyridine; 2-Iodonicotinonitrile; 3-Pyridinecarbonitrile, 2-iodo-; 2-Iodo-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Iodonicotinonitrile 98 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity verification. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.