Description

1-(5-Chloro-1,8-naphthyridin-2-yl)ethanone is a high-purity organic compound featuring a fused naphthyridine core, a key structural motif in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and research chemical for the development of novel active ingredients. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to build complex heterocyclic architectures.

Application

• Pharmaceutical Intermediate: A versatile building block for the synthesis of potential drug candidates, particularly those targeting enzymes and receptors where the naphthyridine scaffold is pharmacologically relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Acts as a starting material or ligand in the synthesis of organic electronic materials, metal-organic frameworks (MOFs), or catalysts.
• Chemical Biology Probe: Employed in academic and industrial research to create molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Scale-Up: Serves as a key substrate for contract research and manufacturing organizations (CROs/CMOs) specializing in custom chemical synthesis from milligram to kilogram scale.

Basic Information

Product Name	1-(5-Chloro-1,8-naphthyridin-2-yl)ethanone
CAS No.	488799-77-5
Molecular Formula	C₁₀H₇ClN₂O
Molecular Weight	206.63 g/mol
Synonyms	5-Chloro-2-acetyl-1,8-naphthyridine; 2-Acetyl-5-chloro-1,8-naphthyridine; 1-(5-Chloro-1,8-naphthyridin-2-yl)ethan-1-one; Ethanone, 1-(5-chloro-1,8-naphthyridin-2-yl)-; 5-Chloro-1,8-naphthyridin-2-yl methyl ketone
EINECS	Contact for details

Quality Control

Our production of 1-(5-Chloro-1,8-naphthyridin-2-yl)ethanone adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.