Description

2-Pyridinecarbonitrile, 3-Chloro-5-Nitro- is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates reactive sites for nitrile transformation, electrophilic aromatic substitution, and nitro group reduction, enabling the construction of complex pharmacophores and agrochemical intermediates. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in developing kinase inhibitors, antiviral agents, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its halogen and nitro substituents for bioactivity.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers, coordination complexes, and advanced materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, library synthesis, and exploring new chemical reactions involving nitrile and nitro functionalities.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized heterocyclic dyes and organic pigments due to its aromatic nitro-substituted structure.

Basic Information

Product Name	2-Pyridinecarbonitrile, 3-Chloro-5-Nitro-
CAS No.	488713-30-0
Molecular Formula	C6H2ClN3O2
Molecular Weight	183.55 g/mol
Synonyms	3-Chloro-5-nitropyridine-2-carbonitrile; 3-Chloro-5-nitro-2-cyanopyridine; 2-Cyano-3-chloro-5-nitropyridine; 3-Chloro-5-nitro-2-pyridinecarbonitrile; 3-Chloro-5-nitropicolinonitrile; 2-Pyridinecarbonitrile, 3-chloro-5-nitro-; 3-Chloro-5-nitropyridine-2-carbonitrile (IUPAC); 3-Cl-5-NO2-Py-2-CN
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarbonitrile, 3-Chloro-5-Nitro- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.