Description

Propargyl-Peg1-T-Butyl Ester is a specialized bifunctional chemical building block featuring both a propargyl group and a protected carboxylic acid. This compound is valued for its role in advanced organic synthesis, particularly in click chemistry and bioconjugation strategies. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs) via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Bioconjugation Linker: Used to attach small molecules, dyes, or polymers to biomolecules like proteins, peptides, and oligonucleotides for drug delivery and diagnostic applications.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the synthesis of specialty polymers with tailored properties.
• Agrochemical Synthesis: Employed in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Facilitates the surface functionalization of nanoparticles and other materials to introduce alkyne handles for further modification.
• Chemical Biology Probes: Integral for creating chemical probes to study biological processes and enzyme activity within cells.

Basic Information

Product Name	Propargyl-Peg1-T-Butyl Ester
CAS No.	488150-84-1
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	tert-Butyl 2-(2-propyn-1-yloxy)acetate; 2-(Prop-2-yn-1-yloxy)acetic acid tert-butyl ester; Propargyl-PEG1-t-butyl ester; Propargyl-O-CH2-COOtBu; tert-Butyl (prop-2-yn-1-yloxy)acetate; Propargyloxyacetic acid tert-butyl ester; 2-(Prop-2-ynyloxy)acetic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our Propargyl-Peg1-T-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.