Description

(4-Chloro-5-Formyl-2-Oxo-Thiazol-3-Yl)-Acetic Acid Ethyl Ester is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex thiazole-based molecular architectures. Pharmaceutical R&D and fine chemical manufacturers need this precise chemical to drive innovation in drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those containing the thiazole pharmacophore for potential antimicrobial, anti-inflammatory, or anticancer activity.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its reactive formyl and ester functional groups.
• Organic Synthesis Building Block: Serves as a versatile scaffold in academic and industrial research for constructing complex heterocyclic compounds and functional materials.
• Chemical Research & Development: Employed in method development and exploratory chemistry to create new chemical entities (NCEs) for various high-value applications.

Basic Information

Product Name	(4-Chloro-5-Formyl-2-Oxo-Thiazol-3-Yl)-Acetic Acid Ethyl Ester
CAS No.	487037-12-7
Molecular Formula	C8H6ClNO4S
Molecular Weight	247.66 g/mol
Synonyms	Ethyl (4-chloro-5-formyl-2-oxo-1,3-thiazol-3-yl)acetate; 3-Thiazoleacetic acid, 4-chloro-5-formyl-2-oxo-, ethyl ester; 4-Chloro-5-formyl-2-oxo-3-thiazoleacetic acid ethyl ester; Ethyl 2-(4-chloro-5-formyl-2-oxothiazol-3-yl)acetate; (4-Chloro-5-formyl-2-oxo-2,3-dihydrothiazol-3-yl)acetic acid ethyl ester; CAS 487037-12-7
EINECS	Contact for details

Quality Control

Our (4-Chloro-5-Formyl-2-Oxo-Thiazol-3-Yl)-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.