Description

N'-[1-(3-Methoxyphenyl)-2,5-Dioxo-3-Pyrrolidinyl]Nicotinohydrazide CAS NO 487001-75-2 is a high-purity, specialized heterocyclic organic compound featuring a pyrrolidinedione core linked to nicotinohydrazide and methoxyphenyl moieties. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate for research and development in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs).

Application

This compound serves as a critical building block in sophisticated chemical synthesis. Its primary and potential applications include:

• Pharmaceutical Intermediate: Key precursor in the research and development of new drug candidates, particularly those targeting neurological or inflammatory pathways.
• Medicinal Chemistry Research: Used as a core scaffold or derivatization point for structure-activity relationship (SAR) studies and library synthesis.
• Biochemical Tool Compound: Potential use in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Fine Chemical Synthesis: Intermediate for the production of complex, high-value specialty chemicals with specific biological activities.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	N'-[1-(3-Methoxyphenyl)-2,5-Dioxo-3-Pyrrolidinyl]Nicotinohydrazide
CAS No.	487001-75-2
Molecular Formula	C17H16N4O4
Molecular Weight	340.34 g/mol
Synonyms	N'-[1-(3-Methoxyphenyl)-2,5-dioxopyrrolidin-3-yl]nicotinohydrazide; 3-Methoxyphenylpyrrolidinedione Nicotinoylhydrazone; Nicotinic acid [1-(3-methoxyphenyl)-2,5-dioxo-3-pyrrolidinyl]hydrazide; 1-(3-Methoxyphenyl)-3-(nicotinoylhydrazono)pyrrolidine-2,5-dione; CAS 487001-75-2
EINECS	Contact for details

Quality Control

Our N'-[1-(3-Methoxyphenyl)-2,5-Dioxo-3-Pyrrolidinyl]Nicotinohydrazide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.