Description

Cyclohexanecarboxylic Acid, 3,3-Difluoro-1,4,5-Trihydroxy-, (1R,4S,5R)- (9Ci) is a high-purity, stereochemically defined fluorinated cyclohexane derivative. This compound is a valuable chiral building block and synthetic intermediate, prized for its unique structural features that enable the development of complex molecules with targeted biological activity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas requiring fluorinated, polyhydroxylated scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to modulate the pharmacokinetic and pharmacodynamic properties of potential therapeutics.
• Agrochemical Synthesis: Serves as a sophisticated intermediate in the production of advanced, high-performance crop protection agents and pesticides.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for complex organic molecules in pilot plant and commercial manufacturing.
• Advanced Material Research: Potential precursor for specialty polymers or liquid crystals where fluorination and specific stereochemistry impart desired material properties.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 3,3-Difluoro-1,4,5-Trihydroxy-, (1R,4S,5R)- (9Ci)
CAS No.	486430-84-6
Molecular Formula	C7H10F2O5
Molecular Weight	212.15 g/mol
Synonyms	(1R,4S,5R)-3,3-Difluoro-1,4,5-trihydroxycyclohexanecarboxylic acid; (1R,4S,5R)-3,3-Difluoro-1,4,5-trihydroxycyclohexane-1-carboxylic acid; 3,3-Difluoro-1,4,5-trihydroxycyclohexanecarboxylic acid (1R,4S,5R)-isomer; Fluorinated Cyclohexane Triol Carboxylic Acid; Chiral Difluorocyclohexane Derivative
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 3,3-Difluoro-1,4,5-Trihydroxy-, (1R,4S,5R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.