Description

4-(N,N-Dimethylaminosulfonyl)Phenylboronic Acid Pinacol Ester is a high-value, organoboron building block featuring a protected boronic acid group and a dimethylaminosulfonyl substituent. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex biaryl structures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to introduce functionalized aromatic fragments into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing sulfonamide and biaryl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific aromatic coupling for bioactivity.
• Material Science Research: Serves as a precursor in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological systems and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs serving the life sciences industry.

Basic Information

Product Name	4-(N,N-Dimethylaminosulfonyl)Phenylboronic Acid Pinacol Ester
CAS No.	486422-04-2
Molecular Formula	C14H22BNO4S
Molecular Weight	311.21 g/mol
Synonyms	4-(Dimethylsulfamoyl)phenylboronic acid pinacol ester; [4-(N,N-Dimethylsulfamoyl)phenyl]boronic acid pinacol ester; 4-(Dimethylsulfamoyl)benzeneboronic acid pinacol ester; Pinacol [4-(N,N-dimethylsulfamoyl)phenyl]boronate; B-[4-(Dimethylsulfamoyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(N,N-Dimethylaminosulfonyl)benzeneboronic acid pinacol ester; CAS 486422-04-2
EINECS	Contact for details

Quality Control

Our 4-(N,N-Dimethylaminosulfonyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with each shipment, detailing batch-specific results. Our quality commitment aligns with the standards required for research and development use in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.