Description

2-(3-Chloropyridin-4-Yl)Acetonitrile is a versatile and high-value pyridine-based nitrile building block, essential for advanced organic synthesis. Its molecular structure, featuring both a chloropyridine ring and an acetonitrile moiety, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the chloropyridine scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its reactive nitrile group.
• Chemical Biology Probes: Utilized to build molecular probes and tags for studying biological processes and target identification.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-(3-Chloropyridin-4-Yl)Acetonitrile
CAS No.	485828-87-3
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	4-(Cyanomethyl)-3-chloropyridine; 3-Chloro-4-pyridineacetonitrile; (3-Chloro-4-pyridinyl)acetonitrile; 3-Chloro-4-(cyanomethyl)pyridine; 2-(3-Chloro-4-pyridinyl)acetonitrile; 4-(2-Cyanoethyl)-3-chloropyridine (incorrect but common misnomer); 3-Chloropyridine-4-acetonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Chloropyridin-4-Yl)Acetonitrile is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.