Description

1-(6-Chloropyridin-3-Yl)Cyclobutanecarbonitrile is a high-value, synthetically versatile nitrile-substituted cyclobutane derivative. This compound serves as a critical advanced pharmaceutical intermediate and a key building block in modern organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation insecticides and herbicides, leveraging its chloropyridine moiety.
• Chemical Research & Development: Serves as a versatile building block for constructing complex, strained-ring systems in medicinal chemistry and material science projects.
• Ligand and Catalyst Development: The nitrile and pyridine functional groups make it a candidate for developing novel ligands in coordination chemistry and catalysis.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring specific cyclobutane frameworks.

Basic Information

Product Name	1-(6-Chloropyridin-3-Yl)Cyclobutanecarbonitrile
CAS No.	485828-75-9
Molecular Formula	C10H9ClN2
Molecular Weight	192.65 g/mol
Synonyms	1-(6-Chloro-3-pyridinyl)cyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-(6-chloro-3-pyridinyl)-; 1-(6-Chloropyridin-3-yl)cyclobutanecarbonitrile; 485828-75-9; 1-(6-Chloro-pyridin-3-yl)-cyclobutanecarbonitrile; 1-(6-Chloro-3-pyridyl)cyclobutanecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-(6-Chloropyridin-3-Yl)Cyclobutanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.