Description

5H-1,2,3-Triazolo[4,5-C]Pyridine-5-Carboxaldehyde,1,4,6,7-Tetrahydro-1- is a high-purity, advanced pharmaceutical intermediate characterized by its fused triazolo-pyridine heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel, complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies due to its versatile aldehyde functional group and heterocyclic core.
• Bioconjugation & Probe Development: The reactive aldehyde moiety makes it suitable for creating fluorescent probes, affinity labels, or antibody-drug conjugates (ADCs) for diagnostic and therapeutic applications.
• Agrochemical Research: Employed in the research and development of new crop protection agents, leveraging its heterocyclic scaffold for bioactivity.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	5H-1,2,3-Triazolo[4,5-C]Pyridine-5-Carboxaldehyde,1,4,6,7-Tetrahydro-1-
CAS No.	485402-53-7
Molecular Formula	C7H8N4O
Molecular Weight	164.16 g/mol
Synonyms	1,4,6,7-Tetrahydro-5H-[1,2,3]triazolo[4,5-c]pyridine-5-carboxaldehyde; 5H-[1,2,3]Triazolo[4,5-c]pyridine-5-carboxaldehyde, 1,4,6,7-tetrahydro-; 1,4,6,7-Tetrahydro-5H-1,2,3-triazolo[4,5-c]pyridine-5-carbaldehyde; Triazolopyridine carboxaldehyde derivative; CAS 485402-53-7
EINECS	Contact for details

Quality Control

Our production of 5H-1,2,3-Triazolo[4,5-C]Pyridine-5-Carboxaldehyde,1,4,6,7-Tetrahydro-1- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We support development and commercial projects with material produced under a cGMP-compliant quality system where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material at 2-8°C under an inert atmosphere to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.