Description

Cyclopropanecarboxamide, 2-(3-Pyridinyl)-, (1R,2R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral compound, identified by CAS number 484654-41-3. This molecule serves as a critical advanced pharmaceutical intermediate (API intermediate) or building block in the synthesis of complex, biologically active molecules. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams for developing new therapeutic agents, particularly in areas requiring specific enantiomeric control.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and development of novel active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used in catalytic and stoichiometric asymmetric synthesis to introduce the cyclopropane moiety with defined stereochemistry.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands or organocatalysts.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in pharmaceutical manufacturing.

Basic Information

Item	Details
Product Name	Cyclopropanecarboxamide, 2-(3-Pyridinyl)-, (1R,2R)-Rel- (9Ci)
CAS No.	484654-41-3
Molecular Formula	C9H10N2O
Molecular Weight	162.19 g/mol
Synonyms	(1R,2R)-2-(Pyridin-3-yl)cyclopropanecarboxamide; (1R,2R)-2-(3-Pyridyl)cyclopropanecarboxamide; rel-(1R,2R)-2-(3-Pyridinyl)cyclopropanecarboxamide; (1R,2R)-2-(3-Pyridinyl)cyclopropanecarboxamide; (1R,2R)-2-(Pyridin-3-yl)cyclopropanecarboxylic acid amide; 2-(3-Pyridinyl)cyclopropanecarboxamide, (1R,2R)-rel-; (1R,2R)-rel-2-(3-Pyridinyl)cyclopropanecarboxamide
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxamide, 2-(3-Pyridinyl)-, (1R,2R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.