Description

Cyclopropanemethanol, 2-(4-Pyridinyl)-, (1R,2R)-Rel- (9Ci) is a high-purity chiral building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclopropane ring and a pyridine moiety, makes it a valuable intermediate for constructing complex molecules with specific three-dimensional architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the stereochemistry of the cyclopropane ring is critical for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or functional additive for creating polymers with specialized optical or electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.

Basic Information

Product Name	Cyclopropanemethanol, 2-(4-Pyridinyl)-, (1R,2R)-Rel- (9Ci)
CAS No.	484654-36-6
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(1R,2R)-2-(Pyridin-4-yl)cyclopropanemethanol; (1R,2R)-2-(4-Pyridyl)cyclopropylmethanol; rel-(1R,2R)-2-(4-Pyridinyl)cyclopropanemethanol; (1R,2R)-2-(4-Pyridinyl)cyclopropanemethanol; 2-(4-Pyridinyl)-((1R,2R)-cyclopropyl)methanol; (1R,2R)-2-(4-Pyridyl)cyclopropanecarbinol
EINECS	Contact for details

Quality Control

Our Cyclopropanemethanol, 2-(4-Pyridinyl)-, (1R,2R)-Rel- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, essential for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical purity (typically >97% by HPLC), and identity confirmation. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.