Description

Cyclopropanecarboxamide, 2-(4-Pyridinyl)-, (1R,2R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral compound that serves as a critical synthetic intermediate in advanced pharmaceutical research. Its value lies in its unique cyclopropane and pyridine-containing scaffold, which is instrumental in the development of novel bioactive molecules targeting specific receptors and enzymes. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and biotechnology industries, particularly for the synthesis of potential drug candidates in areas such as oncology and neurology.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Asymmetric Synthesis: Employed as a precursor or reagent in stereoselective synthesis due to its defined (1R,2R) relative configuration.
• Biochemical Probe Development: Useful for creating tool compounds to study biological pathways and protein-ligand interactions.
• Process Chemistry: Serves as a starting material for scaling up the production of complex drug candidates under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical market.

Basic Information

Product Name	Cyclopropanecarboxamide, 2-(4-Pyridinyl)-, (1R,2R)-Rel- (9Ci)
CAS No.	484654-26-4
Molecular Formula	C9H10N2O
Molecular Weight	162.19 g/mol
Synonyms	(1R,2R)-2-(Pyridin-4-yl)cyclopropanecarboxamide; rel-(1R,2R)-2-(4-Pyridyl)cyclopropanecarboxamide; (1R,2R)-2-(4-Pyridinyl)cyclopropanecarboxamide; 2-(4-Pyridinyl)cyclopropanecarboxamide, (1R,2R)-rel-; Cyclopropanecarboxamide, 2-(4-pyridinyl)-, (1R,2R)-rel-; (1R,2R)-rel-2-(4-Pyridinyl)cyclopropanecarboxamide
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxamide, 2-(4-Pyridinyl)-, (1R,2R)-Rel- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We commit to specifications that meet the rigorous standards required for medicinal chemistry and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.