Description

4-(Chloromethyl)-2-(Naphthalen-2-Yl)Pyridine CAS NO 482376-26-1 is a high-value, multi-functional organic building block featuring a pyridine core substituted with a reactive chloromethyl group and a naphthalene moiety. This compound matters for its versatility as a key intermediate in the synthesis of complex molecules, particularly in advanced material science and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or acting as kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the naphthalene-pyridine scaffold can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, luminescent materials, and other advanced functional polymers.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes due to its modifiable chloromethyl handle.
• Custom Synthesis & Contract Manufacturing: A key building block for custom synthesis houses serving the life sciences and electronics industries.

Basic Information

Product Name	4-(Chloromethyl)-2-(Naphthalen-2-Yl)Pyridine
CAS No.	482376-26-1
Molecular Formula	C₁₇H₁₄ClN
Molecular Weight	267.75 g/mol
Synonyms	2-(2-Naphthyl)-4-(chloromethyl)pyridine; 4-(Chloromethyl)-2-(2-naphthyl)pyridine; 2-(Naphthalen-2-yl)-4-(chloromethyl)pyridine; 4-Chloromethyl-2-naphthalen-2-yl-pyridine; 2-Naphthalen-2-yl-4-chloromethylpyridine; 482376-26-1; 4-(Chloromethyl)-2-naphthalen-2-ylpyridine
EINECS	Contact for details

Quality Control

Our 4-(Chloromethyl)-2-(Naphthalen-2-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.