Description

Carbamic Acid, (3-Hydroxy-2-Methylpropyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized carbamate derivative used as a key building block in advanced organic synthesis. This compound matters for its role as a protected intermediate, enabling the controlled introduction of functional groups in complex molecule construction. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a protected amino-alcohol functionality.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its structural motif can contribute to biological activity.
• Peptide Mimetics & PROTACs: Acts as a versatile linker or spacer in the design of peptide mimetics and Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
• Polymer Chemistry: Can be utilized as a monomer or chain modifier in the production of specialty polyurethanes and polycarbonates with tailored properties.
• Chemical Biology Probes: Employed in the creation of molecular probes and labeled compounds for studying biological pathways and mechanisms.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Carbamic Acid, (3-Hydroxy-2-Methylpropyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	480451-99-8
Molecular Formula	C9H19NO3
Molecular Weight	189.25 g/mol
Synonyms	1,1-Dimethylethyl N-(3-hydroxy-2-methylpropyl)carbamate; tert-Butyl (3-hydroxy-2-methylpropyl)carbamate; (3-Hydroxy-2-methylpropyl)carbamic acid tert-butyl ester; N-(3-Hydroxy-2-methylpropyl)carbamic acid tert-butyl ester; tert-Butoxycarbonylamino-2-methylpropan-3-ol; Boc-3-amino-2-methyl-1-propanol; Boc-NH-(CH2)2CH(OH)CH3 (abbrev.); 480451-99-8
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (3-Hydroxy-2-Methylpropyl)-, 1,1-Dimethylethyl Ester (9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.