Description

3-((tert-Butyl(Diphenyl)Silyl)Oxy)-2,2-Dimethylpropanoic Acid is a high-purity, protected carboxylic acid derivative widely used as a key synthetic intermediate in advanced organic chemistry. Its primary value lies in its role as a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide & Prodrug Synthesis: Used for the protection of carboxylic acid groups during complex peptide coupling and prodrug design strategies.
• Agrochemical Research: Serves as a key intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the synthesis of specialized monomers and polymers with tailored properties.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and molecular probes for biochemical research.
• Process Chemistry: Valued in scale-up and optimization of synthetic routes for commercial manufacturing.

Basic Information

Product Name	3-((tert-Butyl(Diphenyl)Silyl)Oxy)-2,2-Dimethylpropanoic Acid
CAS No.	480450-04-2
Molecular Formula	C21H28O3Si
Molecular Weight	356.53 g/mol
Synonyms	2,2-Dimethyl-3-[(2-methyl-2-phenyl-1-sila-1,1-diphenylpropyl)oxy]propanoic Acid; 3-[(tert-Butyldiphenylsilyl)oxy]-2,2-dimethylpropanoic Acid; TBDPS-protected 2,2-Dimethyl-3-hydroxypropanoic Acid; tert-Butyl(diphenyl)silyl 2,2-Dimethyl-3-hydroxypropionate Acid; TBDPS-DMPA; CAS 480450-04-2
EINECS	Contact for details

Quality Control

Our 3-((tert-Butyl(Diphenyl)Silyl)Oxy)-2,2-Dimethylpropanoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.