Description

(2-Fluorophenylethynyl)Trimethylsilane is a specialized organosilicon building block featuring a fluorinated aromatic alkyne moiety protected by a trimethylsilyl (TMS) group. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, particularly in cross-coupling and cycloaddition reactions. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity, functionalized intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, including kinase inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, leveraging the metabolic stability imparted by the fluorine atom.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional materials.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands for transition metal catalysis and organometallic complexes.
• Organic Electronic Materials: A precursor for synthesizing conjugated molecules and polymers used in OLEDs and other electronic devices.
• Fluorine Chemistry Research: A valuable reagent for studying Sonogashira coupling and other palladium-catalyzed reactions with fluorinated substrates.

Basic Information

Item	Details
Product Name	(2-Fluorophenylethynyl)Trimethylsilane
CAS No.	480439-33-6
Molecular Formula	C11H13FSi
Molecular Weight	192.31 g/mol
Synonyms	1-(Trimethylsilyl)-2-fluoroethynylbenzene; 2-Fluoroethynylbenzene trimethylsilyl ether; 2-Fluorophenylacetylene trimethylsilyl derivative; TMS-Protected 2-Fluorophenylacetylene; Trimethyl(2-fluorophenylethynyl)silane; 2-Fluoro-((trimethylsilyl)ethynyl)benzene; (o-Fluorophenylethynyl)trimethylsilane
EINECS	Contact for details

Quality Control

Our (2-Fluorophenylethynyl)Trimethylsilane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.