Description

Methyl 3-Isocyanato-2-Methylbenzoate is a versatile and reactive chemical intermediate featuring both an isocyanate and an ester functional group. This dual functionality makes it a valuable building block for synthesizing more complex molecules, particularly in the development of advanced materials and active pharmaceutical ingredients. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a benzoate ester and isocyanate-derived linkages, such as in certain protease inhibitors or kinase inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where its reactive isocyanate group enables the formation of urea or carbamate moieties.
• Polymer & Resin Modification: Serves as a cross-linking agent or chain extender in polyurethane systems, contributing to the thermal and mechanical properties of specialty coatings, adhesives, and elastomers.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring novel heterocyclic compounds, peptidomimetics, and other fine chemicals.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and pigments, leveraging its aromatic structure.

Basic Information

Product Name	Methyl 3-Isocyanato-2-Methylbenzoate
CAS No.	480439-28-9
Molecular Formula	C10H9NO3
Molecular Weight	191.18 g/mol
Synonyms	3-Isocyanato-2-methylbenzoic acid methyl ester; Methyl 2-methyl-3-isocyanatobenzoate; 2-Methyl-3-isocyanatobenzoic acid methyl ester; Benzoic acid, 3-isocyanato-2-methyl-, methyl ester; Methyl o-tolyl-3-isocyanate-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Isocyanato-2-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation and maintain reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.