Description

3-Bromo-2,4,6-Trimethylphenyl Isocyanate is a specialized aromatic isocyanate building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of high-performance materials and active pharmaceutical ingredients (APIs), where its unique brominated and sterically hindered structure imparts specific reactivity and properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its structure can be incorporated into active molecules.
• Polymer Modification: Acts as a reactive monomer or cross-linking agent for producing specialized polyurethanes and polyurea coatings with enhanced properties.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new organic reactions and synthesizing complex heterocycles.
• Material Science: Used to develop advanced functional materials with specific optical or electronic characteristics.

Basic Information

Product Name	3-Bromo-2,4,6-Trimethylphenyl Isocyanate
CAS No.	480439-19-8
Molecular Formula	C10H10BrNO
Molecular Weight	240.10 g/mol
Synonyms	3-Bromo-2,4,6-trimethylphenyl isocyanate; 2,4,6-Trimethyl-3-bromophenyl isocyanate; 1-Bromo-2,4,6-trimethyl-3-isocyanatobenzene; Isocyanic acid, 3-bromo-2,4,6-trimethylphenyl ester; 3-Bromo-2,4,6-trimethylbenzenisocyanate; (3-Bromo-2,4,6-trimethylphenyl)isocyanate
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,4,6-Trimethylphenyl Isocyanate is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.