Description

3-Bromo-4-Methoxyphenethyl Isocyanate is a specialized aromatic isocyanate building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional reactivity, where the isocyanate group enables the formation of ureas and carbamates, while the bromo and methoxy substituents on the aromatic ring offer versatile sites for further functionalization. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex molecular scaffolds, developing active pharmaceutical ingredients (APIs), and creating novel polymer precursors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its aromatic structure for bioactive molecule design.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polyurethanes and polyurea coatings with tailored properties.
• Chemical Research & Development: A versatile reagent for exploring new organic reactions and constructing complex heterocyclic compounds in academic and industrial R&D settings.
• Material Science: Employed in the synthesis of advanced materials, such as liquid crystals or functional polymers, where specific aromatic and isocyanate functionalities are required.
• Bioconjugation: Potential use in modifying biomolecules or surfaces through its reactive isocyanate group for diagnostic or sensor applications.

Basic Information

Product Name	3-Bromo-4-Methoxyphenethyl Isocyanate
CAS No.	480439-05-2
Molecular Formula	C10H10BrNO2
Molecular Weight	256.10 g/mol
Synonyms	2-(3-Bromo-4-methoxyphenyl)ethyl isocyanate; 1-Bromo-2-methoxy-4-(2-isocyanatoethyl)benzene; 3-Bromo-4-methoxy-β-isocyanatoethylbenzene; 3-Bromo-4-methoxyphenethyl isocyanate; 480439-05-2; Phenethyl isocyanate, 3-bromo-4-methoxy-; 2-(3-Bromo-4-methoxyphenyl)ethan-1-yl isocyanate
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Methoxyphenethyl Isocyanate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles. Our commitment to quality supports your R&D and scale-up processes with reliable, specification-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.