Description

5-Bromo-2-Methoxyphenethyl Isocyanate is a specialized aromatic isocyanate building block of significant interest in advanced organic synthesis. Its core value proposition lies in its bifunctional reactivity, where the isocyanate group enables the formation of ureas and carbamates, while the bromo and methoxy substituents on the aromatic ring offer versatile sites for further functionalization. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active molecules, as well as by material scientists exploring advanced polymers and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for the development of polyurethanes, polyureas, and other specialty polymers with tailored properties.
• Chemical Biology & Bioconjugation: Utilized as a reactive handle for labeling biomolecules or modifying surfaces due to the high reactivity of the isocyanate group with amines and alcohols.
• Liquid Crystal & OLED Material Research: Acts as a precursor for synthesizing complex organic molecules with potential electronic or photonic applications.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CROs/CMOs serving the life sciences sector.

Basic Information

Product Name	5-Bromo-2-Methoxyphenethyl Isocyanate
CAS No.	480439-04-1
Molecular Formula	C10H10BrNO2
Molecular Weight	256.10 g/mol
Synonyms	2-(5-Bromo-2-methoxyphenyl)ethyl isocyanate; 1-(5-Bromo-2-methoxyphenyl)-2-isocyanatoethane; 5-Bromo-2-methoxy-β-isocyanatoethylbenzene; 5-Bromo-2-methoxyphenethyl isocyanate; (5-Bromo-2-methoxyphenyl)ethyl isocyanate; 2-(5-Bromo-2-methoxyphenyl)ethanamine, NCO derivative; Isocyanic acid, (5-bromo-2-methoxyphenethyl) ester
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methoxyphenethyl Isocyanate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We support cGMP compliance for advanced intermediates and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.