Description

8-tert-Butyl 3-Ethyl 1-Oxa-2,8-Diazaspiro[4.5]Dec-2-Ene-3,8-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and metabolic disorder research pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Serves as a core structural component in the manufacturing process of complex target molecules for preclinical and clinical trials.
• Chemical Biology Probes: Employed in the development of specialized probes and tools for studying biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical companies with custom synthesis and scale-up services.
• Academic Research: Utilized in university and institutional labs for pioneering research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	8-tert-Butyl 3-Ethyl 1-Oxa-2,8-Diazaspiro[4.5]Dec-2-Ene-3,8-Dicarboxylate
CAS No.	479636-65-2
Molecular Formula	C16H26N2O5
Molecular Weight	326.39 g/mol
Synonyms	tert-Butyl 3-ethyl 1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3,8-dicarboxylate; 1-Oxa-2,8-diazaspiro[4.5]dec-2-ene-3,8-dicarboxylic acid, 3-ethyl 8-(1,1-dimethylethyl) ester; 8-(tert-Butoxycarbonyl)-3-ethoxycarbonyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene; 3-Ethyl 8-tert-butyl 1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3,8-dicarboxylate; BOC-DOA Spiro Ester; CAS 479636-65-2
EINECS	Contact for details

Quality Control

Our 8-tert-Butyl 3-Ethyl 1-Oxa-2,8-Diazaspiro[4.5]Dec-2-Ene-3,8-Dicarboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our production adheres to cGMP guidelines where applicable, ensuring suitability for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.