Description

2H-Pyrrolo[2,3-B]Pyridin-2-One, 1,3-Dihydro-1-[(4-Methylphenyl)Sulfonyl]- is a high-purity, advanced pharmaceutical intermediate with the CAS number 479553-02-1. This compound is a critical building block in the synthesis of complex heterocyclic molecules, offering significant value in research and development for novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in oncology and neurology.
• Kinase Inhibitor Synthesis: Serves as a core scaffold for the preparation of potent and selective kinase inhibitors.
• Chemical Biology Research: Used as a probe or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Process Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	2H-Pyrrolo[2,3-B]Pyridin-2-One, 1,3-Dihydro-1-[(4-Methylphenyl)Sulfonyl]-
CAS No.	479553-02-1
Molecular Formula	C14H12N2O3S
Molecular Weight	288.32 g/mol
Synonyms	1-Tosyl-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one; 1,3-Dihydro-1-[(4-methylphenyl)sulfonyl]-2H-pyrrolo[2,3-b]pyridin-2-one; 1-(4-Methylphenyl)sulfonyl-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one; 1-(p-Toluenesulfonyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one; 479553-02-1; Pyrrolo[2,3-b]pyridin-2-one derivative; Tosyl-pyrrolopyridinone
EINECS	Contact for details

Quality Control

Our 2H-Pyrrolo[2,3-B]Pyridin-2-One, 1,3-Dihydro-1-[(4-Methylphenyl)Sulfonyl]- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.