Description

2-(3,4,5-Trimethoxyphenyl)-1H-Pyrrolo[2,3-B]Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolopyridine core functionalized with a trimethoxyphenyl group. This compound is of significant value in medicinal chemistry research and development, serving as a critical building block for novel drug candidates. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged scaffold.
• Kinase Inhibitor Development: Serves as a core structure for the design and development of potential kinase inhibitors, given the pyrrolopyridine motif's relevance in this class.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological processes and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	2-(3,4,5-Trimethoxyphenyl)-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	479551-35-4
Molecular Formula	C₁₆H₁₆N₂O₃
Molecular Weight	284.31 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridine, 2-(3,4,5-trimethoxyphenyl)-; 2-(3,4,5-Trimethoxyphenyl)-7-azaindole; 2-(3,4,5-Trimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridine; 2-(3,4,5-Trimethoxyphenyl)-7-aza-indole; 7-Azaindole, 2-(3,4,5-trimethoxyphenyl)-; 2-(3,4,5-Trimethoxyphenyl)-1H-7-azaindole
EINECS	Contact for details

Quality Control

Our 2-(3,4,5-Trimethoxyphenyl)-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.