Description

3-Pyridinecarboxylicacid,6-[[(2S)-2-Pyrrolidinylcarbonyl]Amino]-,Methylester is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the development of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Protease Inhibitor Research: Used in the development of inhibitors for various proteolytic enzymes due to its pyrrolidine and pyridine motifs.
• Chiral Synthesis: Serves as a chiral precursor for creating enantiomerically pure compounds in asymmetric synthesis.
• Ligand and Catalyst Development: Employed in the design of novel ligands and organocatalysts for chemical transformations.
• Bioconjugation Chemistry: Its reactive ester group makes it suitable for conjugation with biomolecules like peptides or proteins.
• Academic and Industrial R&D: A valuable reagent for exploratory research in organic and medicinal chemistry laboratories.

Basic Information

Product Name	3-Pyridinecarboxylicacid,6-[[(2S)-2-Pyrrolidinylcarbonyl]Amino]-,Methylester
CAS No.	478913-95-0
Molecular Formula	C13H15N3O3
Molecular Weight	261.28 g/mol
Synonyms	Methyl 6-[[(2S)-2-pyrrolidinylcarbonyl]amino]nicotinate; (S)-Methyl 6-(pyrrolidine-2-carboxamido)nicotinate; 6-[(L-Prolinamido)]nicotinic Acid Methyl Ester; L-Pro-Nic-OMe; 478913-95-0; Methyl 6-((S)-pyrrolidine-2-carboxamido)nicotinate; Nicotinic acid, 6-[[(2S)-2-pyrrolidinylcarbonyl]amino]-, methyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure identity, potency, and purity meet exacting standards. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept in a desiccated environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.