Description

Cyclohexanecarboxylic Acid, 3-Amino-, Methyl Ester, (1R,3R)-Rel- (9Ci) is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry makes it a critical building block for the development of enantiomerically pure pharmaceuticals and agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers engaged in the synthesis of complex, biologically active molecules, where precise stereochemical control is paramount for efficacy and regulatory approval.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and insecticides, where the specific stereoisomer can enhance activity and reduce environmental impact.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in academic and industrial research focused on developing new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, specialty chemicals requiring a specific (1R,3R) stereochemical configuration.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and verification in chiral separation techniques like HPLC.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 3-Amino-, Methyl Ester, (1R,3R)-Rel- (9Ci)
CAS No.	478694-53-0
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	(1R,3R)-rel-3-Aminocyclohexanecarboxylic acid methyl ester; Methyl (1R,3R)-rel-3-aminocyclohexanecarboxylate; Methyl 3-aminocyclohexanecarboxylate (rel-(1R,3R)-); (1R,3R)-3-Amino-cyclohexanecarboxylic acid methyl ester; rel-(1R,3R)-Methyl 3-aminocyclohexanecarboxylate; 3-Aminocyclohexanecarboxylic Acid Methyl Ester (rel-(1R,3R)-); Methyl trans-3-aminocyclohexanecarboxylate (relative configuration)
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 3-Amino-, Methyl Ester, (1R,3R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (rel-(1R,3R)-)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.