Description

2-Piperidinecarboxylic Acid, 5-Hydroxy-, (2S)- (9Ci) is a high-purity chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for the development of novel pharmaceuticals and bioactive molecules, particularly those targeting the central nervous system. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in neurological and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the production of advanced, enantioselective pesticides and herbicides where specific stereochemistry is required for efficacy and environmental safety.
• Biochemical Research: Serves as a precursor or standard in biochemical studies, including enzyme inhibition assays and metabolic pathway investigations.
• Peptidomimetics & Drug Design: Employed as a constrained amino acid analog in the design of peptide-like molecules (peptidomimetics) to enhance stability and bioavailability.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel chiral catalysts and ligands used in asymmetric synthesis.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various industrial and research applications.

Basic Information

Product Name	2-Piperidinecarboxylic Acid, 5-Hydroxy-, (2S)- (9Ci)
CAS No.	478409-64-2
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	(2S)-5-Hydroxypipecolic Acid; L-5-Hydroxypipecolic Acid; (2S)-5-Hydroxy-2-piperidinecarboxylic Acid; 5-Hydroxy-L-pipecolic Acid; 5-Hydroxy-(S)-pipecolic Acid; (S)-5-Hydroxypipecolic Acid; 5-Hydroxy-L-pipecolate; (2S,5S)-5-Hydroxypipecolic Acid (stereoisomer)
EINECS	Contact for details

Quality Control

Our 2-Piperidinecarboxylic Acid, 5-Hydroxy-, (2S)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) documenting identity, purity, and chiral excess are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.