Description

tert-Butyl 4-(6-Aminopyridin-2-yl)piperidine-1-carboxylate is a high-purity, protected piperidine derivative featuring a key aminopyridine moiety. This compound serves as a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex bioactive molecules, particularly in drug discovery programs targeting central nervous system and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small molecule therapeutics.
• Drug Discovery Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its piperidine and aminopyridine pharmacophores.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of complex, proprietary compounds for clients in the life sciences sector.
• Academic & Institutional Research: Used in university and government labs for fundamental research in organic chemistry and heterocyclic compound development.

Basic Information

Product Name	tert-Butyl 4-(6-Aminopyridin-2-yl)piperidine-1-carboxylate
CAS No.	478366-40-4
Molecular Formula	C15H23N3O2
Molecular Weight	277.36 g/mol
Synonyms	1-Boc-4-(6-Amino-2-pyridyl)piperidine; tert-Butyl 4-(6-amino-2-pyridinyl)-1-piperidinecarboxylate; 4-(6-Aminopyridin-2-yl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(6-aminopyridin-2-yl)piperidine; BOC-4-(6-Aminopyridin-2-yl)piperidine; 2-(1-Boc-4-piperidyl)-6-aminopyridine; N-Boc-4-(6-aminopyridin-2-yl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(6-Aminopyridin-2-yl)piperidine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with the standards expected for GMP-grade intermediates used in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.