Description

1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-4-(4-Nitrophenyl)Piperazine is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyridine and piperazine motifs.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme inhibition and receptor-ligand interactions.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced organic electronic materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations conducting custom synthesis and process optimization for clients.

Basic Information

Product Name	1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-4-(4-Nitrophenyl)Piperazine
CAS No.	478262-11-2
Molecular Formula	C16H12ClF3N4O2
Molecular Weight	384.74 g/mol
Synonyms	4-(4-Nitrophenyl)-1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazine; 1-(3-Chloro-5-trifluoromethyl-2-pyridyl)-4-(4-nitrophenyl)piperazine; 478262-11-2; 1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-4-(4-nitrophenyl)piperazine; 4-(4-Nitrophenyl)-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine; 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(4-nitrophenyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-4-(4-Nitrophenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.