Description

1-(3,4-Difluorobenzyl)-2-Oxo-6-(Trifluoromethyl)-1,2-Dihydro-3-Pyridinecarbonitrile is a high-value, multi-functional heterocyclic building block. Its molecular architecture, featuring difluorobenzyl and trifluoromethyl substituents, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for its role in creating novel compounds with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in therapeutic areas requiring fluorinated molecules for improved metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms contribute to increased efficacy and environmental persistence.
• Material Science Research: Serves as a precursor for developing specialty chemicals, liquid crystals, or organic electronic materials due to its unique electronic properties imparted by the fluorine substituents.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	1-(3,4-Difluorobenzyl)-2-Oxo-6-(Trifluoromethyl)-1,2-Dihydro-3-Pyridinecarbonitrile
CAS No.	478260-56-9
Molecular Formula	C14H7F5N2O
Molecular Weight	314.22 g/mol
Synonyms	1-[(3,4-Difluorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile; 3-Cyano-1-(3,4-difluorobenzyl)-6-(trifluoromethyl)-2(1H)-pyridinone; 6-(Trifluoromethyl)-1-(3,4-difluorobenzyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile; 1-(3,4-Difluorobenzyl)-6-(trifluoromethyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile; 478260-56-9; CAS 478260-56-9
EINECS	Contact for details

Quality Control

Our production of 1-(3,4-Difluorobenzyl)-2-Oxo-6-(Trifluoromethyl)-1,2-Dihydro-3-Pyridinecarbonitrile adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC-MS, and NMR for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.