Description

4-Propionyl-n-[2-(2-Pyridinyl)Ethyl]-1H-Pyrrole-2-Carboxamide CAS NO 478259-53-9 is a high-purity, specialized heterocyclic organic compound featuring a pyrrole-carboxamide core linked to a pyridinyl-ethyl moiety. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and oncological targets.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro and in vivo to study specific biological mechanisms and validate new therapeutic targets.
• Fine Chemical Synthesis: Employed in the production of complex, high-value specialty chemicals for advanced material science applications.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	4-Propionyl-n-[2-(2-Pyridinyl)Ethyl]-1H-Pyrrole-2-Carboxamide
CAS No.	478259-53-9
Molecular Formula	C16H19N3O2
Molecular Weight	285.34 g/mol
Synonyms	4-Propionyl-N-[2-(pyridin-2-yl)ethyl]-1H-pyrrole-2-carboxamide; 1H-Pyrrole-2-carboxamide, 4-propionyl-N-[2-(2-pyridinyl)ethyl]-; 4-Propionyl-N-(2-(pyridin-2-yl)ethyl)-1H-pyrrole-2-carboxamide; Pyrrole-2-carboxamide derivative (CAS 478259-53-9); 2-Pyridineethanamine, N-(4-propionyl-1H-pyrrol-2-yl)carbonyl derivative
EINECS	Contact for details

Quality Control

Our production of 4-Propionyl-n-[2-(2-Pyridinyl)Ethyl]-1H-Pyrrole-2-Carboxamide adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.