Description

3-Benzyl-4-Hydroxy-1-(2-Propynyl)-2(1H)-Pyridinone is a specialized pyridinone derivative with a propargyl functional group, offering unique reactivity for advanced chemical synthesis. This compound serves as a critical building block in pharmaceutical research and development, particularly for creating novel active pharmaceutical ingredients (APIs) and complex molecular scaffolds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to leverage its specific structural motifs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or inflammatory pathways.
• Chemical Biology Probe: Used in research to study enzyme inhibition or protein-ligand interactions due to its specific pyridinone core.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and herbicides.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with tailored properties.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for method development and discovery chemistry.
• Catalyst Ligand Development: Potential use in designing novel ligands for transition metal catalysis.

Basic Information

Product Name	3-Benzyl-4-Hydroxy-1-(2-Propynyl)-2(1H)-Pyridinone
CAS No.	478247-72-2
Molecular Formula	C15H13NO2
Molecular Weight	239.27 g/mol
Synonyms	1-Propargyl-3-benzyl-4-hydroxy-2(1H)-pyridinone; 3-Benzyl-4-hydroxy-1-(prop-2-yn-1-yl)pyridin-2(1H)-one; 1-(2-Propynyl)-3-benzyl-4-hydroxy-2(1H)-pyridinone; BHPP; 4-Hydroxy-3-benzyl-1-(2-propynyl)-2(1H)-pyridinone; 3-Benzyl-1-(prop-2-ynyl)-4-hydroxypyridin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 3-Benzyl-4-Hydroxy-1-(2-Propynyl)-2(1H)-Pyridinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.