Description

2-[(3-Chlorophenyl)Sulfanyl]-4-[3-(Trifluoromethyl)Phenyl]Nicotinonitrile is a high-value, multi-functional heterocyclic compound featuring a nicotinonitrile core substituted with chlorophenylsulfanyl and trifluoromethylphenyl groups. This molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block in modern organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging the biological activity of its structural motifs.
• Material Science Building Block: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and heterocyclic framework.
• Chemical Biology Probe: Acts as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and as a substrate for further functionalization to create complex chemical libraries.

Basic Information

Product Name	2-[(3-Chlorophenyl)Sulfanyl]-4-[3-(Trifluoromethyl)Phenyl]Nicotinonitrile
CAS No.	478245-71-5
Molecular Formula	C19H10ClF3N2S
Molecular Weight	390.81 g/mol
Synonyms	2-[(3-Chlorophenyl)thio]-4-[3-(trifluoromethyl)phenyl]nicotinonitrile; 2-(3-Chlorophenylthio)-4-(3-trifluoromethylphenyl)nicotinonitrile; 4-(3-Trifluoromethylphenyl)-2-(3-chlorophenylthio)nicotinonitrile; Nicotinonitrile, 2-[(3-chlorophenyl)thio]-4-[3-(trifluoromethyl)phenyl]-; 478245-71-5; CAS 478245-71-5
EINECS	Contact for details

Quality Control

Our 2-[(3-Chlorophenyl)Sulfanyl]-4-[3-(Trifluoromethyl)Phenyl]Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.