Description

1,8-Naphthyridine,7-[4-(3-Fluoropropoxy)Phenoxy]-2,4-Bis(Trifluoromethyl)-(9Ci) CAS NO 478081-21-9 is a high-value, fluorinated heterocyclic compound designed for advanced research and development. Its complex structure, featuring multiple trifluoromethyl groups and a fluoropropoxy-phenoxy side chain, makes it a critical building block for synthesizing novel molecules with tailored properties. This compound is primarily sought by pharmaceutical and agrochemical researchers for the development of new active ingredients, where its unique fluorine chemistry can enhance metabolic stability, bioavailability, and binding affinity.

Application

This specialized naphthyridine derivative serves as a key intermediate in sophisticated chemical synthesis. Its primary applications include:

• Pharmaceutical Intermediate: Core building block for the research and development of new drug candidates, particularly in oncology, CNS disorders, and antiviral therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging fluorine's ability to improve lipophilicity and environmental stability.
• Material Science Precursor: Potential intermediate for creating advanced organic electronic materials or specialty polymers with unique fluorinated properties.
• Chemical Biology Probe: Useful in developing molecular probes and tools for studying biological systems due to its distinct structural features.
• Organic Synthesis: A versatile scaffold for medicinal and combinatorial chemistry, enabling the exploration of new chemical space in lead optimization programs.

Basic Information

Product Name	1,8-Naphthyridine,7-[4-(3-Fluoropropoxy)Phenoxy]-2,4-Bis(Trifluoromethyl)-(9Ci)
CAS No.	478081-21-9
Molecular Formula	C20H15F7N2O2
Molecular Weight	448.34 g/mol
Synonyms	7-[4-(3-Fluoropropoxy)phenoxy]-2,4-bis(trifluoromethyl)-1,8-naphthyridine; 2,4-Bis(trifluoromethyl)-7-[4-(3-fluoropropoxy)phenoxy][1,8]naphthyridine; 1,8-Naphthyridine, 7-[4-(3-fluoropropoxy)phenoxy]-2,4-bis(trifluoromethyl)-; CAS 478081-21-9; 7-(4-(3-Fluoropropoxy)phenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine
EINECS	Contact for details

Quality Control

We supply this advanced intermediate under a rigorous quality management system to ensure batch-to-batch consistency and reliability for your critical R&D and scale-up processes. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our production adheres to cGMP principles where applicable, supporting its use in regulated research pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.