Description

2-(2,3-Dimethylphenoxy)-4-Phenylnicotinonitrile is a specialized organic compound belonging to the nicotinonitrile class, serving as a valuable synthetic intermediate and building block in advanced chemical synthesis. Its molecular architecture, featuring a phenyl-substituted pyridine core linked via an ether bridge, makes it a critical precursor for developing novel pharmacologically active molecules and functional materials. This high-purity chemical is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and agrochemical research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science: Serves as a precursor for organic electronic materials, including ligands for metal-organic frameworks (MOFs) or organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Acts as a versatile intermediate for constructing complex polycyclic aromatic systems and functionalized pyridine derivatives.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploratory synthesis projects.

Basic Information

Product Name	2-(2,3-Dimethylphenoxy)-4-Phenylnicotinonitrile
CAS No.	478080-43-2
Molecular Formula	C20H16N2O
Molecular Weight	300.36 g/mol
Synonyms	4-Phenyl-2-(2,3-dimethylphenoxy)nicotinonitrile; 2-(2,3-Dimethylphenoxy)-4-phenyl-3-pyridinecarbonitrile; Nicotinonitrile, 2-(2,3-dimethylphenoxy)-4-phenyl-; 3-Cyano-2-(2,3-dimethylphenoxy)-4-phenylpyridine
EINECS	Contact for details

Quality Control

Our 2-(2,3-Dimethylphenoxy)-4-Phenylnicotinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods such as HPLC, NMR, and MS. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.