Description

2-(Isopropylsulfanyl)-6-(Trifluoromethyl)Nicotinonitrile is a high-purity, advanced pharmaceutical intermediate featuring a nicotinonitrile core with a trifluoromethyl group and an isopropylsulfanyl substituent. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular frameworks. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of agrochemicals and life science products, where its unique structure enables the exploration of new biological activities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides and pesticides, leveraging the biological activity of the pyridine and trifluoromethyl motifs.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex heterocyclic compounds in medicinal and materials chemistry.
• Life Science Reagent: Employed in biochemical research as a tool compound for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	2-(Isopropylsulfanyl)-6-(Trifluoromethyl)Nicotinonitrile
CAS No.	478050-38-3
Molecular Formula	C10H9F3N2S
Molecular Weight	246.25 g/mol
Synonyms	6-(Trifluoromethyl)-2-[(propan-2-yl)sulfanyl]pyridine-3-carbonitrile; 2-Isopropylsulfanyl-6-trifluoromethylnicotinonitrile; 2-[(1-Methylethyl)thio]-6-(trifluoromethyl)-3-pyridinecarbonitrile; 3-Cyano-2-isopropylsulfanyl-6-trifluoromethylpyridine; 2-(Isopropylthio)-6-(trifluoromethyl)nicotinonitrile; 2-(Propan-2-ylsulfanyl)-6-(trifluoromethyl)pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-(Isopropylsulfanyl)-6-(Trifluoromethyl)Nicotinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.