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2-Chloro-6-Cyclopropyl-4-(Trifluoromethyl)Nicotinonitrile CAS NO 478049-48-8


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CAS No.:478049-48-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Chloro-6-Cyclopropyl-4-(Trifluoromethyl)Nicotinonitrile is a high-value, multi-functional chemical intermediate featuring a nicotinonitrile core with halogen and cyclopropyl substituents. This compound matters for its role as a critical building block in the synthesis of advanced active ingredients, particularly in the agrochemical and pharmaceutical sectors. Industries that require the development of novel crop protection agents, such as fungicides and insecticides, as well as research organizations focused on medicinal chemistry, are the primary users of this specialized nitrile.

Application

  • Agrochemical Intermediate: A key precursor in the synthesis of next-generation fungicides and insecticides, leveraging the biological activity of the pyridine and trifluoromethyl motifs.
  • Pharmaceutical Research: Serves as a versatile scaffold in medicinal chemistry for the development of novel drug candidates targeting various diseases.
  • Chemical Synthesis: Used as a building block for constructing more complex heterocyclic compounds due to its reactive nitrile and halogen functional groups.
  • Material Science Research: Potential intermediate in the development of specialty chemicals and functional materials.

Basic Information

Product Name 2-Chloro-6-Cyclopropyl-4-(Trifluoromethyl)Nicotinonitrile
CAS No. 478049-48-8
Molecular Formula C10H6ClF3N2
Molecular Weight 246.62 g/mol
Synonyms 2-Chloro-6-cyclopropyl-4-(trifluoromethyl)pyridine-3-carbonitrile; 2-Chloro-6-cyclopropyl-4-trifluoromethylnicotinonitrile; 3-Cyano-2-chloro-6-cyclopropyl-4-(trifluoromethyl)pyridine; 478049-48-8; Nicotinonitrile, 2-chloro-6-cyclopropyl-4-(trifluoromethyl)-; 2-Chloro-6-cyclopropyl-4-(trifluoromethyl)-3-pyridinecarbonitrile
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Quality Control

Our 2-Chloro-6-Cyclopropyl-4-(Trifluoromethyl)Nicotinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent composition suitable for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Maximum Impurity (HPLC) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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