Description

1,8-Naphthyridine-2-Acetonitrile,α-(4-Methoxyphenyl)-5,7-Bis(Trifluoromethyl)-(9Ci) is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its complex molecular architecture, featuring a naphthyridine core and trifluoromethyl groups, makes it a critical intermediate for developing novel compounds with tailored properties. This specialty chemical is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for targets requiring complex heterocyclic scaffolds.
• Agrochemical Research: Used in developing new active ingredients for crop protection agents, leveraging the bioactivity of the naphthyridine structure.
• Material Science: Acts as a building block for creating advanced organic electronic materials, ligands for catalysis, or specialty polymers.
• Chemical Biology Probe Development: Utilized in designing molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Fluorinated Compound Synthesis: The presence of bis(trifluoromethyl) groups makes it a valuable fluorinated synthon for introducing lipophilicity and metabolic stability into target molecules.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	1,8-Naphthyridine-2-Acetonitrile,α-(4-Methoxyphenyl)-5,7-Bis(Trifluoromethyl)-(9Ci)
CAS No.	478043-31-1
Molecular Formula	C₂₀H₁₁F₆N₃O
Molecular Weight	423.31 g/mol
Synonyms	α-(4-Methoxyphenyl)-5,7-bis(trifluoromethyl)-1,8-naphthyridine-2-acetonitrile; 2-[2-(4-Methoxyphenyl)-5,7-bis(trifluoromethyl)-1,8-naphthyridin-1-ium-1-yl]acetonitrile; 5,7-Bis(trifluoromethyl)-α-(4-methoxyphenyl)-1,8-naphthyridine-2-acetonitrile; 1,8-Naphthyridine-2-acetonitrile, α-(4-methoxyphenyl)-5,7-bis(trifluoromethyl)-; 478043-31-1; (4-Methoxyphenyl)(5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our production of 1,8-Naphthyridine-2-Acetonitrile,α-(4-Methoxyphenyl)-5,7-Bis(Trifluoromethyl)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Residue on Ignition	≤ 0.5 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.