Description

1,8-Naphthyridine-2-Acetonitrile,α-(4-Bromophenyl)-5,7-Bis(Trifluoromethyl)-(9Ci) is a sophisticated, high-value organic building block characterized by its naphthyridine core and multiple halogenated substituents. This compound is critical for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers engaged in cutting-edge molecular design.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders, oncology, and anti-infective applications.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its unique halogenated structure for enhanced bioactivity.
• Material Science: Acts as a building block for creating organic electronic materials, such as ligands for OLEDs or charge-transport molecules, due to its rigid, conjugated framework.
• Chemical Biology Probe: Employed in the design of molecular probes and inhibitors for studying enzyme function and biological pathways in academic and industrial research.
• Coordination Chemistry: Functions as a versatile ligand for metal-organic frameworks (MOFs) or catalysts, utilizing the nitrogen atoms in the naphthyridine ring for metal chelation.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	1,8-Naphthyridine-2-Acetonitrile,α-(4-Bromophenyl)-5,7-Bis(Trifluoromethyl)-(9Ci)
CAS No.	478043-29-7
Molecular Formula	C₁₉H₈BrF₆N₃
Molecular Weight	480.19 g/mol
Synonyms	α-(4-Bromophenyl)-5,7-bis(trifluoromethyl)-1,8-naphthyridine-2-acetonitrile; 2-[2-(4-Bromophenyl)-2-cyanoethyl]-5,7-bis(trifluoromethyl)-1,8-naphthyridine; 478043-29-7; 1,8-Naphthyridine-2-acetonitrile, α-(4-bromophenyl)-5,7-bis(trifluoromethyl)-; (4-Bromophenyl)(5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our production of 1,8-Naphthyridine-2-Acetonitrile,α-(4-Bromophenyl)-5,7-Bis(Trifluoromethyl)-(9Ci) adheres to a stringent quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with ISO standards and meets the exacting requirements of pharmaceutical and advanced material supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. This material is light-sensitive and should be stored away from light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.