Description

1-[4-(tert-Butyl)Benzyl]-4-(Methylsulfanyl)-2-Oxo-6-Phenyl-1,2-Dihydro-3-Pyridinecarbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries need this precise chemical for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides due to its unique pyridine-based core.
• Chemical Biology Probe: Acts as a scaffold for creating tool compounds to study enzyme inhibition and biological pathway modulation.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with specific optical or electronic properties.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and contract research organizations (CROs) for hit-to-lead optimization.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to produce complex, high-value molecules for various industrial applications.

Basic Information

Product Name	1-[4-(tert-Butyl)Benzyl]-4-(Methylsulfanyl)-2-Oxo-6-Phenyl-1,2-Dihydro-3-Pyridinecarbonitrile
CAS No.	478042-83-0
Molecular Formula	C24H24N2OS
Molecular Weight	388.53 g/mol
Synonyms	4-(Methylthio)-1-[(4-tert-butylphenyl)methyl]-2-oxo-6-phenyl-1,2-dihydro-3-pyridinecarbonitrile; 1-[(4-tert-Butylphenyl)methyl]-4-(methylsulfanyl)-2-oxo-6-phenyl-1,2-dihydro-3-pyridinecarbonitrile; 3-Cyano-1-(4-tert-butylbenzyl)-4-(methylthio)-6-phenyl-2(1H)-pyridinone; 1-(4-tert-Butylbenzyl)-4-methylsulfanyl-2-oxo-6-phenyl-1,2-dihydropyridine-3-carbonitrile; CAS 478042-83-0; 1-(4-tert-Butyl-benzyl)-4-methylsulfanyl-2-oxo-6-phenyl-1,2-dihydro-pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 1-[4-(tert-Butyl)Benzyl]-4-(Methylsulfanyl)-2-Oxo-6-Phenyl-1,2-Dihydro-3-Pyridinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure. Handle and store in accordance with all applicable local and international regulations for industrial chemicals.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.