Description

Ethyl 3-Bromo-6-Iodoimidazo[1,2-A]Pyridine-2-Carboxylate is a high-value, multi-halogenated heterocyclic building block crucial for advanced organic synthesis. This compound matters because its unique imidazopyridine core, functionalized with both bromo and iodo substituents, enables precise, sequential cross-coupling reactions, making it indispensable for constructing complex molecular architectures. It is primarily needed by medicinal chemistry and pharmaceutical R&D teams for the development of new active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Agrochemical Development: Employed in creating new active ingredients for crop protection products.
• Material Science: Acts as a building block for organic electronic materials, such as OLED emitters or charge transport layers.
• Chemical Biology: Utilized in the synthesis of molecular probes and tool compounds for biological target validation.
• Catalyst Ligand Synthesis: Provides a scaffold for developing novel ligands used in transition metal catalysis.

Basic Information

Item	Detail
Product Name	Ethyl 3-Bromo-6-Iodoimidazo[1,2-A]Pyridine-2-Carboxylate
CAS No.	478040-70-9
Molecular Formula	C10H8BrIN2O2
Molecular Weight	394.99 g/mol
Synonyms	Ethyl 3-bromo-6-iodoimidazo[1,2-a]pyridine-2-carboxylate; 3-Bromo-6-iodoimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester; Imidazo[1,2-a]pyridine-2-carboxylic acid, 3-bromo-6-iodo-, ethyl ester; 478040-70-9; AI3-53146; AKOS040757548; BRN 12587051; CS-W009767; SCHEMBL2180641; ZINC000257427587
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-6-Iodoimidazo[1,2-A]Pyridine-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and LC-MS. We adhere to cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.