Description

Cyclohexanone, 3-Ethyl-2-[(Trimethylsilyl)Oxy]-, (2R,3S)- (9Ci) is a chiral, organosilicon-protected derivative of cyclohexanone, serving as a sophisticated synthetic intermediate. This compound is valued for its precise stereochemistry, which is critical for controlling the three-dimensional structure and biological activity of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex, optically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system or with complex stereochemical requirements.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereoisomers exhibit enhanced biological efficacy.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Fine Chemical Production: Serves as a versatile intermediate for the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & R&D Laboratories: Utilized in university and corporate research settings for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Item	Detail
Product Name	Cyclohexanone, 3-Ethyl-2-[(Trimethylsilyl)Oxy]-, (2R,3S)- (9Ci)
CAS No.	478015-72-4
Molecular Formula	C11H22O2Si
Molecular Weight	214.38 g/mol
Synonyms	(2R,3S)-3-Ethyl-2-(trimethylsilyloxy)cyclohexanone; (2R,3S)-3-Ethyl-2-[(trimethylsilyl)oxy]cyclohexanone; 3-Ethyl-2-[(trimethylsilyl)oxy]cyclohexanone, (2R,3S)-; (2R,3S)-3-Ethyl-2-(TMS-oxy)cyclohexanone; Cyclohexanone, 3-ethyl-2-[(trimethylsilyl)oxy]-, (2R,3S)-; (2R,3S)-2-(Trimethylsiloxy)-3-ethylcyclohexanone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing specifications such as HPLC/GC purity and chiral purity are available upon request. We adhere to a quality management system suitable for supplying research and development, as well as cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.