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1-(6-Methyl-2-Pyridinyl)-n-(4-Morpholinophenyl)-1H-Imidazole-4-Carboxamide CAS NO 477890-18-9
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CAS No.:477890-18-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-(6-Methyl-2-Pyridinyl)-n-(4-Morpholinophenyl)-1H-Imidazole-4-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant interest for its role in the research and development of novel therapeutic agents, particularly in kinase inhibition pathways. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted drug candidates.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of investigational new drugs (INDs) targeting specific enzyme pathways.
- Kinase Inhibitor Research: Serves as a core scaffold or precursor in the development of potent and selective kinase inhibitors for oncology and inflammatory diseases.
- Biochemical Tool Compound: Used in high-throughput screening (HTS) and in vitro assays to study cellular signaling mechanisms and validate drug targets.
- Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
- Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services for the pharmaceutical industry.
- Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery.
Basic Information
| Product Name | 1-(6-Methyl-2-Pyridinyl)-n-(4-Morpholinophenyl)-1H-Imidazole-4-Carboxamide |
| CAS No. | 477890-18-9 |
| Molecular Formula | C20H21N5O2 |
| Molecular Weight | 363.42 g/mol |
| Synonyms | 1-(6-Methylpyridin-2-yl)-N-[4-(morpholin-4-yl)phenyl]-1H-imidazole-4-carboxamide; 4-Morpholine-N-(4-morpholinophenyl)-1-(6-methyl-2-pyridinyl)-1H-imidazole-2-carboxamide (related isomer); UNII-9K5J6QMF2C; 477890-18-9; 1H-Imidazole-4-carboxamide, 1-(6-methyl-2-pyridinyl)-N-[4-(4-morpholinyl)phenyl]-; Kinase inhibitor intermediate; Morpholinophenyl imidazole carboxamide derivative |
| EINECS | Contact for details |
Quality Control
Our 1-(6-Methyl-2-Pyridinyl)-n-(4-Morpholinophenyl)-1H-Imidazole-4-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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