Description

2-(2,5-Dimethyl-1H-pyrrol-1-yl)-5-iodopyridine is a high-purity, functionalized heterocyclic compound featuring a pyrrole and pyridine scaffold with an iodine substituent. This molecular structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for complex organic synthesis. It is primarily utilized by research institutions and pharmaceutical R&D departments engaged in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Sonogashira) where the iodine atom acts as an excellent leaving group for introducing complex molecular fragments.
• Ligand and Catalyst Development: Employed in the research and preparation of novel ligands for catalysis or metal-organic frameworks (MOFs) due to its nitrogen-rich, bidentate potential.
• Agrochemical Research: Acts as an intermediate in the development of new crop protection agents and pesticides.
• Material Science Research: Investigated for use in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	2-(2,5-Dimethyl-1H-pyrrol-1-yl)-5-iodopyridine
CAS No.	477889-91-1
Molecular Formula	C11H11IN2
Molecular Weight	298.12 g/mol
Synonyms	5-Iodo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine; 2-(2,5-Dimethylpyrrol-1-yl)-5-iodopyridine; 5-Iodo-2-(2,5-dimethylpyrrol-1-yl)pyridine; 2,5-Dimethyl-1-(5-iodopyridin-2-yl)-1H-pyrrole; 1-(5-Iodopyridin-2-yl)-2,5-dimethyl-1H-pyrrole; 477889-91-1
EINECS	Contact for details

Quality Control

Our 2-(2,5-Dimethyl-1H-pyrrol-1-yl)-5-iodopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.