Description

2-Chloro-n-[(2,2-Dimethyl-4,6-Dioxo-1,3-Dioxan-5-Yliden)Methyl]Nicotinamide is a specialized heterocyclic organic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring a nicotinamide core fused with a dioxane-dione moiety, makes it a valuable building block for constructing complex pharmacophores. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of new drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex fused-ring systems and functionalized heterocycles.
• Material Science Research: Potential monomer or additive in the development of specialty polymers with specific optical or electronic properties.
• Academic & Contract Research: Essential for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	2-Chloro-n-[(2,2-Dimethyl-4,6-Dioxo-1,3-Dioxan-5-Yliden)Methyl]Nicotinamide
CAS No.	477885-88-4
Molecular Formula	C14H13ClN2O5
Molecular Weight	324.72 g/mol
Synonyms	5-[(2-Chloronicotinamido)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione; 2-Chloro-N-[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]pyridine-3-carboxamide; 2-Chloronicotinic acid N'-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)hydrazide (tautomeric form); AKD-Intermediate; Meldrum's acid nicotinamide derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-[(2,2-Dimethyl-4,6-Dioxo-1,3-Dioxan-5-Yliden)Methyl]Nicotinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.