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n-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-N'-([(2-Morpholino-2-Oxoethoxy)Amino]Methylene)Thiourea CAS NO 477885-61-3
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CAS No.:477885-61-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-N'-([(2-Morpholino-2-Oxoethoxy)Amino]Methylene)Thiourea is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active ingredients. This compound is critical for research and development in medicinal chemistry, offering a sophisticated scaffold for creating targeted therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drugs, particularly in areas requiring complex heterocyclic structures.
Application
- Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially for targeted therapies.
- Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
- Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation pesticides and herbicides.
- Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
- Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.
- Library Synthesis: A valuable component for creating diverse compound libraries for high-throughput screening in drug discovery.
Basic Information
| Item | Details |
|---|---|
| Product Name | n-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-N'-([(2-Morpholino-2-Oxoethoxy)Amino]Methylene)Thiourea |
| CAS No. | 477885-61-3 |
| Molecular Formula | C15H15ClF3N5O3S |
| Molecular Weight | 449.82 g/mol |
| Synonyms | N-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N'-[(2-morpholin-2-oxoethoxyamino)methylidene]thiourea; 477885-61-3; 3-Chloro-5-(trifluoromethyl)-2-pyridinyl thiourea derivative; Morpholino-oxoethoxy amino methylene thiourea pyridine derivative; (3-Chloro-5-trifluoromethyl-2-pyridyl)thiourea intermediate; CAS 477885-61-3 |
| EINECS | Contact for details |
Quality Control
Our production of n-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-N'-([(2-Morpholino-2-Oxoethoxy)Amino]Methylene)Thiourea adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and consistency.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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