Description

9-[3-Chloro-5-(Trifluoromethyl)-2-Pyridyl]-2,3,4,9-Tetrahydro-1H-3-Carbazolone Ethylene Ketal is a high-value, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, agrochemicals, and other fine chemical products where precise chemical architecture is paramount.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology-related therapeutic areas.
• Agrochemical Research: Serves as a precursor in the development of new-generation pesticides and herbicides, leveraging its pyridine and carbazole motifs.
• Material Science: Potential use in the synthesis of organic electronic materials and photoactive compounds due to its extended conjugated system.
• Chemical Biology: Used as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and target identification.
• Custom Synthesis: Sourced by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring this unique molecular entity.

Basic Information

Product Name	9-[3-Chloro-5-(Trifluoromethyl)-2-Pyridyl]-2,3,4,9-Tetrahydro-1H-3-Carbazolone Ethylene Ketal
CAS No.	477873-13-5
Molecular Formula	C23H19ClF3N2O2
Molecular Weight	456.86 g/mol
Synonyms	9-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,3,4,9-tetrahydro-1H-carbazol-3-one ethylene ketal; 9-(3-Chloro-5-trifluoromethyl-2-pyridyl)-2,3,4,9-tetrahydro-1H-3-carbazolone ethylene ketal; 1H-Carbazol-3-one, 9-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2,3,4,9-tetrahydro-, ethylene ketal; CAS 477873-13-5; 9-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-one ethylene ketal; 477873-13-5; Ethylene ketal of 9-[3-chloro-5-(trifluoromethyl)-2-pyridyl]-2,3,4,9-tetrahydro-1H-3-carbazolone
EINECS	Contact for details

Quality Control

Our production of 9-[3-Chloro-5-(Trifluoromethyl)-2-Pyridyl]-2,3,4,9-Tetrahydro-1H-3-Carbazolone Ethylene Ketal adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with customer specifications and relevant industry guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.