Description

1-[(2,4-Dichlorophenyl)Sulfonyl]-1H-Pyrrolo[2,3-B]Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonylated pyrrolopyridine core structure. This compound is of significant value for its role as a key building block in the research and development of novel therapeutic agents, particularly in kinase inhibitor programs. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Chemical Biology Research: Used as a molecular scaffold or probe in structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Agrochemical Development: Serves as a potential intermediate for creating novel active ingredients with specific biological activity.
• Material Science Research: Investigated for its potential in creating specialized organic electronic materials or ligands for catalysis due to its electron-rich heterocyclic system.

Basic Information

Product Name	1-[(2,4-Dichlorophenyl)Sulfonyl]-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	477872-33-6
Molecular Formula	C13H8Cl2N2O2S
Molecular Weight	335.18 g/mol
Synonyms	1-(2,4-Dichlorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 1-[(2,4-dichlorophenyl)sulfonyl]-; 1-(2,4-Dichloro-benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; Pyrrolo[2,3-b]pyridine, 1-[(2,4-dichlorophenyl)sulfonyl]-; CAS 477872-33-6
EINECS	Contact for details

Quality Control

Our production of 1-[(2,4-Dichlorophenyl)Sulfonyl]-1H-Pyrrolo[2,3-B]Pyridine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory documentation needs for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.