Description

Ethyl 5-Cyano-6-[(4-Methylbenzyl)Amino]-2-Phenylnicotinate is a high-value, functionalized nicotinate derivative serving as a critical advanced intermediate in modern synthetic chemistry. This compound is engineered to provide a versatile chemical scaffold for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides due to its functionalized pyridine core.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of libraries of compounds for high-throughput screening.
• Material Science: Potential intermediate in the synthesis of organic electronic materials and ligands for catalytic systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations requiring high-purity, complex intermediates for custom synthesis projects.

Basic Information

Product Name	Ethyl 5-Cyano-6-[(4-Methylbenzyl)Amino]-2-Phenylnicotinate
CAS No.	477866-21-0
Molecular Formula	C23H21N3O2
Molecular Weight	371.44 g/mol
Synonyms	Ethyl 5-cyano-6-[(4-methylbenzyl)amino]-2-phenylpyridine-3-carboxylate; 2-Pyridinecarboxylic acid, 5-cyano-6-[(4-methylphenyl)methyl]amino]-, ethyl ester; 5-Cyano-6-[(4-methylbenzyl)amino]-2-phenylnicotinic acid ethyl ester; Ethyl 6-[(4-methylbenzyl)amino]-5-cyano-2-phenylnicotinate; 477866-21-0; Ethyl 5-cyano-6-(p-methylbenzylamino)-2-phenylnicotinate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Cyano-6-[(4-Methylbenzyl)Amino]-2-Phenylnicotinate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.